pqq depletes glutathione does deplete Full article: Recent progress in studies on the health benefits of pyrroloquinoline quinone Pyrroloquinoline Quinone Frontiers | Mitochondrial ROS dyshomeostasis:

Interestingly, compared with the controls at day 7 and day 14, both L-NAME and L-arginine increased MDA values, and when given together, L-NAME and L-arginine antagonised each other

Organic Acid Testing: Brain Fog, Anxiety & Fatigue Quick Answer Organic Acid Testing (OAT) is a functional urine test used in integrative medicine to measure metabolic by-products, including markers of gut microbial activity, mitochondrial function, neurotransmitter metabolism, and oxidative stress

10.1002/sim.1186 [DOI] [PubMed] [Google Scholar] Houle S

Again, yes

Picking the volume that makes the dose hit 10 / 20 / 25 / 50 units removes a class of arithmetic errors